Reinstatement of methamphetamine conditioned place preference in nicotine-sensitized rats
نویسندگان
چکیده
منابع مشابه
Effects of Acute and Chronic Restraint Stress on Reinstatement of Extinguished Methamphetamine-induced Conditioned Place Preference in Rats
Introduction: Methamphetamine (METH) is a neurotoxic psychostimulant with highly addictive potential that leads to compulsive drug use and vulnerability to relapse. Environmental cues, such as drug exposure, peer influence, and social stress, are the powerful triggers of drug relapse. In this study, we tried to find out the effect of acute and chr...
متن کامل[Rewarding property of nicotine and methamphetamine tested by conditioned place preference in rats: effect of chronic nicotine pretreatment].
Nicotine is classified as a dependence-producing drug. This study investigated the rewarding property of nicotine employing the conditioned place preference (CPP) paradigm in a three-compartment box, and compared it with that of methamphetamine (MAP). In place conditioning using a biased method, rats were placed in one (white or black) compartment under the drug treatment and placed in the othe...
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Objective: It has been shown that berberine, a major component of Berberis vulgaris extract, modulates the activity of several neurotransmitter systems including dopamine (Da) and N-methyl-D-aspartate (NMDA) contributing to rewarding and reinforcing effects of morphine. Drug craving and relapsing even after a long time of abstinence therapy are the most important problems of addiction. In the p...
متن کاملEffects of bupropion on the reinstatement of nicotine-induced conditioned place preference by drug priming in rats.
Nicotine is one of the most widely consumed psychoactive drugs, and its consumption is currently associated with other drugs of abuse, such as opioids. The aim of the present study was to evaluate the efficacy of the atypical antidepressant drug bupropion (5, 10 and 20 mg/kg, ip) in blocking the reinstatement of nicotine-induced conditioned place preference (CPP) provoked by nicotine and morphi...
متن کاملEffect of linalool on the acquisition and reinstatement of morphine-induced conditioned place preference in mice
Objective: The effect of linalool, a terpene alcohol found in many plants, which inhibits NMDA receptors, on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) was evaluated in mice.Material and Methods: The effects of different doses of linalool (12.5, 25 and 50 mg/kg, i.p.), memantine (20 mg/kg, an NMDA receptor antagonist) and saline, in CPP induced by 4...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2012
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2012.07.043